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Canada: “World first ever drone delivery of lungs”

By Chris Stonor

The drone was only making a short journey — about six minutes — from Toronto Western Hospital to Toronto General Hospital, but the University Health Network’s surgeon-in-chief knew its cargo would make the trip historic and time was of the essence, reports

Nestled inside a lightweight, carbon fibre container and suspended from a Unither Bioelectronique drone was a set of lungs destined for Shaf Keshavjee’s patient, a male engineer to be operated on. Keshavjee recalled, “To see it come over the tall buildings was a very exciting moment. I certainly did breathe a sigh of relief, when it landed and I was able to see that everything was OK.”

Shaf Keshavjee

The trip was the first in the world for lungs to be delivered by drone and after this successful flight, some believe this could become the norm as the speed to deliver human organs is of the essence.

The first to complete the feat was the University of Maryland Medical Center in Baltimore, when a drone-delivered kidney was transplanted in 2019. Since then, MissionGo and Nevada Donor Network sent corneas on a five-minute flight and a kidney on a 25-minute journey and in May, a pancreas took to Minnesota’s skies. Keshavjee continued, “It’s very much like the first airplane flight. That didn’t go very far, but it really opened the door to what airplane travel is today,”

While drone transportation for human organs may seem a little odd, doctors and health businesses believe technology is crucial to improve outcomes for Canadians with organ diseases. Last year, 2,622 Canadians received transplants, 4,129 were on waiting lists and 276 died before an organ came available.

Unither Bioelectronique parent company United Therapeutics has been determined to slash that wait-list since the firm was started by Sirius Satellite Radio co-founder, Martine Rothblatt, in 1996, after her daughter was diagnosed with pulmonary arterial hypertension.

The world is woefully short of organ donors and faster deliveries mean fragile and temperature-sensitive organs have a smaller chance of deteriorating and transplants have better odds of lasting.

Lungs are particularly challenging. They were one of the last organs to be successfully transplanted in humans in 1983 in Toronto and 80 percent of those offered for donation are unusable because they don’t meet oxygenation, X-ray or function standards.

Drone and biotechnology companies are more determined than ever to reduce that expense and inefficiency. Aside from Unither Bioelectronique and MissionGo, U.S. companies AD Airlines and AlarisPro Transport and China’s EHang are all working on making organ drone flights common.

Mikael Cardinal, Unither Bioelectronique’s Vice-President of program management for organ delivery systems, agreed that rivals can be empowering, but knows their collective goal isn’t easy. He said, “It takes courage to be the first to do something like this, but that courage needs to come with the highest standard of safety.”

Martine Rothblatt

His team prepared for the Toronto flight for 18 months. Before they received clearance to fly the drone in a busy area, they designed a container to withstand changes in elevation, barometric pressure, vibrations and other jarring events. There were practice flights loaded with dummy packages simulating lungs and even drop tests for the final drone and container, which were outfitted with a parachute and advanced GPS system.

Meanwhile, Rothblatt selected Toronto General Hospital because it was first to successfully complete a lung and double lung transplant. She explained, “I felt that the karma of the universe would be right if the first-ever drone transplant was also done at Toronto General Hospital.”

Keshavjee was eager to get involved and had several patients hoping to be the recipient. He chose a drone enthusiast, whose recovery is going well. But his and United’s work is far from over. The company’s website shows it has 14 health projects underway, with many expecting results in the near or short-term.

Rothblatt concluded, “There’s so many problems in the world like climate change, war, just endless problems, but to be able to wake up each morning and just smile and say, ‘wow, another life was saved that day’… It gives me a sense of fulfilment.”

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